The palace, built in the middle of the sixteenth century by the Sylos family, has a large porch in Renaissance style. It’s located in the centre of the town. The entrance portal, in ashlar, is decorated with two medallions with imperial effigies and an inscription praising Christ. It currently houses the National Gallery "G. e R. Devanna".
F. Moretti, V. Robles, Cultura e società a Bitonto nell'Ottocento, Edipuglia, 2003. G. Pavone, V. Sblendorio, Bitonto. Nell’arte e nella storia, cinque itinerari per un Borgo Antico da riscoprire, Regione Puglia. Assessorato alla Pubblica Istruzione CRSEC BA8-BITONTO, Bitetto 2000.